Identification and Analysis of Essential Genes in Streptococcus mutans with Transposon Sequencing
Walker AR & Shields RC
Essential Genes and Genomes


Repurposing the Streptococcus mutans CRISPR-Cas9 system to understand essential gene function
Shields RC, Walker AR, Maricic N, Chakraborty B, Underhill SAM, & Burne RA
PLOS Pathogens

Peptides encoded in the Streptococcus mutans RcrRPQ operon are essential for thermotolerance
Shields RC, Kim JN, Ahn SJ, & Burne RA


Carbohydrate and PepO control bimodality in competence development by Streptococcus mutans
Underhill SAM, Shields RC, Burne RA, & Hagen SJ
Molecular Microbiology

Fluorescence tools adapted for monitoring the behaviors of Streptococcus species
Shields RC, Kaspar JR, Underhill SAM, Lee K, & Burne RA
Applied and Environmental Microbiology

The bare necessities: uncovering essential and condition-critical genes with transposon sequencing
Shields RC & Jensen PA
Molecular Oral Microbiology


Intracellular signaling by the comRS system in Streptococcus mutans genetic competence
Underhill SAM, Shields RC, Kaspar JR, Haider M, Burne RA, & Hagen SJ

Competence inhibition by the XrpA peptide encoded within the comX gene of Streptococcus mutans
Kaspar JR, Shields RC, & Burne RA
Molecular Microbiology

Genomewide identification of essential genes and fitness determinants of Streptococcus mutans UA159
Shields RC, Zeng L, Culp DJ, & Burne RA

Genome-wide screens reveal new gene products that influence genetic competence in Streptococcus mutans
Shields RC, O’Brien G, Maricic N, Kesterson AE, Grace M, Hagen SJ, & Burne RA
Journal of Bacteriology


Intercellular communication via the comX-inducing peptide (XIP) of Streptococcus mutans
Kaspar JR, Underhill SAM, Shields RC, Reyes A, Rosenzweig S, Hagen SJ, & Burne RA
Journal of Bacteriology

A new arginine-based dental adhesive system: formulation, mechanical and anti-caries properties
Geraldeli S, Soares EF, Alvarez AJ, Tanaz F, Shields RC, Sinhoreti, MAC, & Nascimento MM
Journal of Dentistry

A critical role for extracellular DNA in dental plaque formation
Rostami N, Shields RC, Yassin SA, Hawkins AR, Bowen L, Luo TL, Rickard AH, Holliday R, Preshaw PM, & Jakubovics NS
Journal of Dental Research


Growth of Streptococcus mutans in biofilms alters peptide signalling at the sub-population level
Shields RC, & Burne RA
Frontiers in Microbiology


Bidirectional signalling in the competence regulatory pathway of Streptococcus mutans
Son M, Shields, RC, Ahn, SJ, Burne, RA, & Hagen, SJ
FEMS Microbiology Letters

Conserved and divergent functions of RcrRPQ in Streptococcus gordonii and Streptococcus mutans
Shields RC, & Burne RA
FEMS Microbiology Letters

Biofilms in chronic rhinosinusitis: what is new and where next?
Ramakrishnan Y, Shields RC, Elbadawey MR, & Wilson JR
The Journal of Laryngology and Otology


Life after death: the critical role of extracellular DNA in microbial biofilms
Jakubovics NS, Shields RC, Rajarajan N, & Burgess JG
Letters in Applied Microbiology

Efficacy of a marine bacterial nuclease against biofilm forming microorganisms isolated from chronic rhinosinusitis
Shields RC, Mokhtar N, Ford M, Hall MJ, Burgess JG, ElBadawey MR, & Jakubovics NS


Removal of biofilms from tracheoesophageal speech valves using a novel marine microbial deoxyribonuclease
Shakir A, Elbadawey MR, Shields RC, Jakubovics NS, & Burgess JG
Otolaryngology and Head and Neck Surgery